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Semaglutide outperforms other GLP-1 drugs for weight loss in psychiatric populations

Researchers found semaglutide produced the largest weight loss in a 9-trial review of 595 psychiatric patients, but said larger trials are needed.

Summary by News Medical
A network meta-analysis of nine randomized controlled trials found that once-weekly semaglutide showed the largest estimated weight-loss effect among GLP-1 receptor agonists tested in adults with mental illness and obesity or related metabolic risk. The authors cautioned that the findings remain preliminary because the evidence base was small, heterogeneous, and largely indirect.

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Psychology Today broke the news in New York, United States on Thursday, July 9, 2026.
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