Scientists find a weak spot in deadly fungus that shut down hospital intensive care units

Scientists find a weak spot in deadly fungus that shut down hospital intensive care units

A deadly hospital fungus that resists nearly every antifungal drug may have an unexpected weakness. Researchers discovered that Candida auris activates specific genes during infection to hunt for nutrients it needs to survive. This insight came from a new living-host model that allowed scientists to watch the fungus in action. The findings could eventually lead to new treatments or allow current drugs to be repurposed.

Carbonic Anhydrase Nce103 Drives Candida Auris Resistance

In a groundbreaking study poised to reshape our understanding of the formidable fungal pathogen Candida auris, researchers have unveiled the crucial role of the enzyme carbonic anhydrase Nce103 in orchestrating both the skin colonization preferences and antifungal resistance mechanisms of this emerging global health threat. Candida auris, notorious for its rapid spread in healthcare settings and its alarming resistance to multiple antifungal age…

New findings on Candida auris open up potential targets for future therapies

23.12.2025 - A new study involving the Medical University of Vienna shows how the multi-resistant fungus Candida auris utilises carbon dioxide (CO2) to survive on the skin and become resistant to antifungal therapies. The research team identified several new targets that could be used in the future to curb the spread and infections caused by Candida auris. Due to its rapid development of resistanc