Revolutionary Breakthrough in the Hunt for Hidden HIV Sparks Hope for a Cure

New antibody studies boost hope for HIV cure

Pioneering trials discover potential strategy to keep virus in check after stopping treatment

Revolutionary Breakthrough in the Hunt for Hidden HIV Sparks Hope for a Cure

Researchers at Icahn School of Medicine have developed a groundbreaking technique to detect dormant HIV within immune cells. The HIV-1-induced lineage tracing (HILT) system uses a genetic switch to reveal hidden viral reservoirs by changing cell color from red to green. This method targets HIV’s elusive hiding spots within CD4 T cells, a major barrier to finding a definitive cure. Analysis of over 47,000 T cells identified nine types harboring l…

New Method Marks Immune Cells Where HIV Lies Dormant

Researchers from the Icahn School of Medicine at Mount Sinai have developed a new method to genetically tag immune cells that carry HIV, allowing them to study the reservoir of immune cells where the virus hides. The study, published in Nature Communications, represents a step forward in the development of curative therapies for HIV, which affects nearly 40 million people globally. Antiretroviral therapies are effective at halting the spread of …