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Researchers find DMT provides longer-lasting antidepressant effects than S-ketamine in animal models

Summary by PsyPost
A recent study published in the journal Neuropharmacology provides evidence that a single dose of the psychedelic compound N,N-dimethyltryptamine can produce rapid and long-lasting antidepressant effects in mice. The research suggests that this naturally occurring hallucinogen might also reduce anxiety, offering a potential advantage over existing fast-acting treatments like S-ketamine. These findings highlight the promise of psychedelic compoun…

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PsyPost broke the news on Wednesday, April 15, 2026.
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