Single Vaccine Could Protect Against All Respiratory Pathogens

Single vaccine could protect against all respiratory pathogens

Early research raised hopes for a vaccine that would protect against all respiratory pathogens simultaneously, rather than just a single disease such as influenza. Traditional vaccines prime the immune system for specific targets, such as a protein on a virus. The new system, delivered via nasal spray, boosts the system’s communication signals, putting it on a higher alert. In mice, the spray reduced infection rates from viruses including flu an…

Single vaccine could protect against all coughs, colds and flus, researchers say

(BBC) – A single nasal spray vaccine could protect against all coughs, colds and flus, as well as bacterial lung infections, and may even ease allergies, say US researchers. The team at Stanford University have tested their “universal vaccine” in animals and still need to do human clinical trials. Their approach marks a “radical departure” from the way vaccines have been designed for more than 200 years, they say. Experts in the field said the s…

Mucosal Vaccination in Mice Provides Protection from Diverse Respiratory Threats

Investigators described an intranasal liposomal formulation combining toll-like receptor 4 and 7/8 ligands with a model antigen, ovalbumin, that provided broad, durable protection in mice for at least 3 months against infection with SARS-CoV-2 and Staphylococcus aureus. [Science] Abstract

One vaccine may provide broad protection against many respiratory infections and allergens

In the realm of medical advancements, a universal vaccine that can protect against any pathogen has long been a Holy Grail — and about as elusive as a mythological vessel. But Stanford Medicine researchers and collaborators have taken an astonishing step forward in that quest, surprising even themselves. In a new study in mice, they have developed a universal vaccine formula that protects against a wide range of respiratory viruses, bacteria and…