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Real Madrid vs RB Leipzig Champions League preview: All you need to know
Real Madrid are strong favorites after scoring 13 goals in their last five matches, while RB Leipzig arrive after a 6-1 Bundesliga defeat.
On Wednesday, October 21, 2026, Real Madrid hosts RB Leipzig at the Santiago Bernabeu in a Champions League match, with kickoff at 20:00 GMT and Madrid entering as strong favorites.
Leipzig seeks recovery following a heavy 6-1 defeat to Bayern Munich, contrasting sharply with Real Madrid's recent form of scoring four goals in each of their last two outings.
Manager Jose Mourinho welcomes back Vinicius Junior from suspension, while Kylian Mbappe leads the attack after scoring twice against Sevilla in Madrid's recent 4-1 victory.
Analysts predict a comfortable Real Madrid win with a 4-1 scoreline, though Leipzig threatens through Christopher Nkunku and Antonio Nusa, who have combined for nine goals this season.
Madrid sits eighth in the Champions League standings while Leipzig occupies 21st, positioning Real Madrid to advance before facing Barcelona in El Clasico next.
Real Madrid are chasing a third Champions League win when they host RB Leipzig on Thursday (October 22, 2026) early morning WIB. Los Blancos have significant capital.