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For Oprah Winfrey, a Croissant Is Now Just a Croissant — Not a Struggle

Oprah Winfrey credits GLP-1 drugs for weight loss and an unexpected loss of alcohol desire, improving her energy and self-confidence, she told People magazine.

  • On Dec. 30, Oprah Winfrey told People she stopped drinking alcohol after using GLP-1 weight-loss medication, which she began two and a half years ago.
  • After decades of weight struggle, Winfrey shifted her view and sought GLP-1 treatment after saying she was pre-diabetic with high cholesterol at 211 lbs and collaborated with Dr. Ania M. Jastreboff on a book due Jan. 13.
  • After briefly stopping the shots in early 2024, Winfrey regained weight despite diet and exercise, and now plans lifelong use with weekly injections and a magnesium supplement and hydration routine.
  • Framing it as a public service, Winfrey urged people with obesity not to blame themselves and said she wants them to have information to choose treatment or dieting, noting partner Stedman Graham has been supportive.
  • With a pill due early 2026, experts note that more than 100 weight-loss medications are in development, while Dr. Drew said, `If we have a medication that can be helpful, by all means, people should be encouraged to think about it.
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Oprah Winfrey has revealed that the weight-loss drug GLP-1, which she started taking in 2023, has suddenly reduced her desire to drink alcohol. In a new interview with People, the OWN founder opened up about how the drug, which she has been taking for about two and a half years, has transformed her relationship with food and exercise, in addition to eliminating her taste for alcohol. “The fact that I don’t have a craving for it anymore is really…

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NBC Miami broke the news in Miami, United States on Tuesday, December 30, 2025.
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