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Novartis grabs kidney drug developer Regulus in $1.7bn deal

  • Novartis agreed to acquire San Diego-based Regulus Therapeutics for up to $1.7 billion on Wednesday, including $800 million upfront.
  • The agreement comes after Regulus developed farabursen, an experimental microRNA-targeted therapy for a hereditary kidney disorder characterized by cyst formation, which completed a Phase 1b clinical trial in 2023.
  • Regulus investors will be paid $7 per share upfront in cash, with the possibility of an additional $7 per share contingent on achieving regulatory approval, representing a premium exceeding 100% over the stock’s previous closing price.
  • Novartis's chief medical officer Shreeram Aradhye stated that farabursen could offer 'enhanced efficacy, tolerability and safety' for ADPKD patients with limited treatment options.
  • The acquisition aligns with Novartis's kidney disease strategy and is expected to close in second half of 2025, integrating Regulus into its global research and development system.
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channelchek.com broke the news in on Wednesday, April 30, 2025.
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