Novartis grabs kidney drug developer Regulus in $1.7bn deal
- Novartis agreed to acquire San Diego-based Regulus Therapeutics for up to $1.7 billion on Wednesday, including $800 million upfront.
- The agreement comes after Regulus developed farabursen, an experimental microRNA-targeted therapy for a hereditary kidney disorder characterized by cyst formation, which completed a Phase 1b clinical trial in 2023.
- Regulus investors will be paid $7 per share upfront in cash, with the possibility of an additional $7 per share contingent on achieving regulatory approval, representing a premium exceeding 100% over the stock’s previous closing price.
- Novartis's chief medical officer Shreeram Aradhye stated that farabursen could offer 'enhanced efficacy, tolerability and safety' for ADPKD patients with limited treatment options.
- The acquisition aligns with Novartis's kidney disease strategy and is expected to close in second half of 2025, integrating Regulus into its global research and development system.
12 Articles
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Novartis to acquire San Diego-based Regulus in deal worth up to $1.7B
Swiss pharmaceutical giant Novartis is poised to expand its profile in the San Diego area, announcing plans to acquire Regulus Therapeutics, a local company on the cusp of bringing a potential breakthrough treatment for kidney disease onto the market. In a deal with total equity value of up to $1.7 billion, a subsidiary of Novartis will merge with Regulus in an offer that is expected to close in the second half of this year. Among the medicines …
Novartis to acquire Regulus in $1.7B kidney drug deal
The basics: Novartis to acquire Regulus for up to $1.7 billion Deal adds ADPKD candidate farabursen to pipeline Target brings proprietary microRNA drug platform Novartis plans to acquire clinical stage biotech Regulus Therapeutics in a deal worth up to $1.7 billion. Under the terms announced April 30, the Swiss drugmaker will make an upfront payment of $800 million to the San Diego-based company. If Regulus’ lead drug candidate, farabursen, get…
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