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Merus Stock Surges Over 35% On Strong Phase 2 Cancer Trial Results: What's Going On? - Merus (NASDAQ:MRUS)

  • Merus reported interim phase 2 trial results on May 22, 2025, showing petosemtamab with pembrolizumab improves outcomes in head and neck cancer patients.
  • The trial included 43 patients with PD-L1 positive advanced or returning head and neck squamous cell cancer and investigated a combination treatment approach aimed at improving current therapeutic outcomes.
  • The treatment achieved a 63% overall response rate including six complete and 21 partial responses, with a 79% 12-month survival rate and median progression-free survival of nine months.
  • Merus shares rose 34.9% to $56.11 amid favorable market reactions, while price targets increased to $88 and $110, and no significant overlapping toxicities were reported.
  • These promising results suggest petosemtamab could become a new standard of care pending phase 3 trial data expected in 2026, with durable responses and manageable safety observed so far.
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Inside Ottawa Valley broke the news in Ottawa, Canada on Thursday, May 22, 2025.
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