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Medical AI startup OpenEvidence doubles valuation to $12 billion in latest round

OpenEvidence's ad-supported AI chatbot for doctors reached $100 million annual revenue and 18 million clinical consultations in December, led by Thrive Capital and DST.

  • On Jan 21, 2026, OpenEvidence closed a $250 million Series D at a $12 billion valuation, co-led by Thrive Capital and DST Global.
  • To scale product specialization, OpenEvidence plans to build an orchestra of smaller specialist medical models focusing on oncology, radiology, and neurology, while monetizing its advertising revenue model after crossing $100 million annually.
  • Clinician adoption has grown rapidly, with about 740,000 physicians—about 45% of doctors in the United States—using the platform and supporting 18 million clinical consultations last month.
  • The company says its recent fundraising brings total capital raised to roughly the high hundreds of millions, with Daniel Nadler's net worth doubling to $7.6 billion and Zachary Ziegler holding a 7.3% stake worth $875 million.
  • The financing positions OpenEvidence to accelerate specialist models in a $5 trillion U.S. health-care market, with Nadler saying real-world clinical consultations serve as a key moat amid competition from OpenAI and Anthropic.
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Refresh Miami broke the news on Wednesday, January 21, 2026.
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