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Environmental Triggers as Significant as Genetics for Disease Development
Up to 90% of disease incidence is linked to environmental and social exposures, with new technologies enabling comprehensive lifetime exposure mapping.
- Exposomics is emerging as a new framework to map lifetime exposures, with the AAMC reporting that up to 90% of disease incidence is influenced by environmental, biological, and social factors.
- The $7.7 million NIH grant helped establish the Network for Exposomics in the United States last year, as experts estimate genetic mutations cause only about 10% of some diseases.
- Advanced chemical analyses and satellite-derived geospatial data enable collection of thousands of markers in blood or urine, while Stanford Medicine's 'exposometer' gathers chemical and biological samples directly from wearers.
- Researchers envision exposomic profiles being added to electronic medical records to help physicians move beyond guesswork toward personalized environmental-risk assessments, NEXUS co-leader Rima Habre said.
- As an enormous project, exposomics faces infrastructure and coordination challenges, requiring collaboration among researchers across genetics, environmental science and data science, with the human genome mapping analogy guiding the 'exposome' concept.
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59 Articles
Environmental triggers as significant as genetics for disease development
Experts estimate that genetic mutations account for about 10% of diseases, like Parkinson's, for example. The remaining 90% are thought to be caused by environmental factors, prompting scientists to look beyond genetics.
·Washington, United States
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Total News Sources59
Leaning Left8Leaning Right11Center14Last UpdatedBias Distribution43% Center
Bias Distribution
- 43% of the sources are Center
43% Center
L 24%
C 43%
R 33%
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