Low‑dose Oral Lithium May Help Slow the Decline of Verbal Memory, Trial Suggests
A pilot trial at University of Pittsburgh found low-dose lithium slowed verbal memory decline in 80 older adults with mild cognitive impairment, especially amyloid-positive cases.
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Can Lithium Protect the Aging Brain?
(MedPage Today) -- Daily lithium carbonate showed a promising signal in the pilot LATTICE trial of older adults with mild cognitive impairment, but failed to meet a prespecified significance threshold for any of six coprimary outcomes compared...
Pilot Clinical Trial Indicates Low-Dose Lithium Could Slow Decline in
For decades, lithium has been a cornerstone treatment for bipolar disorder, primarily recognized for its mood-stabilizing properties. However, recent exploratory research from the University of Pittsburgh is unveiling a compelling new facet of this venerable drug: its potential neuroprotective effects in the domain of cognitive decline associated with Alzheimer’s disease. This emerging evidence suggests that […]
Pilot clinical trial suggests low dose lithium may slow verbal memory decline
Lithium—a decades-old treatment for bipolar disorder—may hold potential neuroprotective benefits beyond mood stabilization. An exploratory clinical trial from the University of Pittsburgh suggests that low‑dose oral lithium may help slow the decline of verbal memory, or ability to remember and recall words and sentences, in older adults with mild cognitive impairment, particularly among those with evidence of amyloid beta—one of the hallmark bio…
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