Low-Dose Radiation Shows Lasting Benefits in Patients with Knee Osteoarthritis
The therapy was linked to a 67% lower adjusted hazard of disability and fewer knee replacements in grade 2 patients, researchers said.
- Researchers at the American Society for Radiation Oncology presented a 12-year study of 292 patients in Russia suggesting low-dose radiation therapy may offer sustained pain relief and potentially slow knee osteoarthritis progression.
- "Radiation therapy works differently at very low doses," said Dr. Bobby Koneru, radiation oncologist at Loyola University Chicago, explaining that these lower amounts target inflammation inside the joint rather than killing cells like cancer treatments.
- Data across the study population showed a 67% lower adjusted hazard of disability, while MRI scans tracked for three years revealed structural improvements, particularly among 78 patients with grade 2 disease.
- Comparing outcomes, disability developed in 31% of radiation-treated patients versus 61% receiving medication alone, while knee replacement surgery occurred in 14% versus 36% of the respective groups.
- Experts like Dr. Gopal K. Bajaj, co-chair of the Functional Radiation Medicine Task Force, noted the findings warrant further investigation, as larger, rigorously controlled multicenter trials are needed before changing clinical practice.
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This European treatment for joint pain just passed a major scientific test
Korean researchers found that low-dose radiation therapy eased knee pain and improved movement in people with mild to moderate osteoarthritis. The treatment, far weaker than cancer radiation, showed real benefits beyond placebo. With no side effects and strong trial results, the approach could provide a middle ground between painkillers and joint surgery.
Dr. Vincent Valinducq tells us about a new approach to treating knee osteoarthritis, using radiation therapy to slow the progression of the disease. Approximately 30% of patients aged 65 to 75 are affected. (Health and well-being).
A long-term study has shown that low-dose radiation therapy can help ease the pain of knee coarseness, and maintain a detailed function for a longer period of time.
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