Intensive Diet and Exercise Program Puts 54% of Young Adults With Type 2 Diabetes Into Remission
Researchers said the program also preserved muscle and improved fitness, while only 4% of standard-care patients reached remission.
- A long-term study found that 58% of participants assigned to weight-loss surgery achieved type 2 diabetes remission during follow-up, compared with 3% of those assigned to intensive medical and lifestyle management.
- Remission, defined as maintaining A1C levels below 6.5% without medication, raises a central question about which treatment approaches offer patients the best chance of reaching and sustaining this goal.
- Lead author Donald Simonson, M.D., MPH, identified that participants with shorter diabetes duration, no insulin use, and significant early weight loss were most likely to achieve lasting remission.
- Identifying these predictors allows physicians at the OU Harold Hamm Diabetes Center to offer the procedure to eligible patients earlier, rather than as a last resort.
- While the ARMMS-T2D Study suggests metabolic surgery improves longer-term outcomes over 11 years, principal investigator John P. Kirwan, Ph.D., emphasizes that continued monitoring remains essential to ensure remission endures.
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29 Articles
Could Type 2 Diabetes Be Reversed? 14-Year Study Reveals Remarkable Results
In a long-term trial, weight-loss surgery led to more type 2 diabetes remissions than intensive medical and lifestyle management, while patients’ disease histories offered clues to who might benefit most. For some people with type 2 diabetes, keeping blood sugar under control without medication is possible. This state, known as remission, raises a question that [...]
NEW research shows that diet and exercise can lead to remission of type 2 diabetes in adults.
A low-calorie diet and exercise helped 54% of younger adults achieve diabetes remission
In a randomized clinical trial involving 96 adults with early-onset type 2 diabetes and obesity, a 24-week program combining a low-energy diet with supervised exercise achieved diabetes remission in 54% of participants, compared with 4% receiving usual care. The intervention also reduced body fat, largely preserved muscle mass, and improved strength and body-mass-adjusted fitness, although the additional benefits attributable specifically to exe…
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