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Read Before You Reheat: The Real Deadline for Eating, Storing Thanksgiving Leftovers

Toxicologist Brad Reisfeld advises refrigerating leftovers within two hours and consuming most cooked foods within three to four days to prevent foodborne illness.

  • On the Colorado State University podcast, toxicologist Brad Reisfeld, PhD, urged home cooks and consumers to prioritize timing, temperature and common sense soon to avoid holiday food poisoning.
  • Health experts note that bacteria multiply fastest in the ‘‘danger zone’’ between 40°F and 140°F, increasing spoilage and illness risk if leftovers remain at unsafe temperatures.
  • For common dishes, experts note that most leftovers should be eaten within two to four days, turkey and large cooked meats last three to four days, cranberry sauce lasts seven days, and pumpkin pie must be eaten within two to three days.
  • To reduce immediate risk, refrigerate or freeze leftovers within two hours in shallow airtight containers and reheat to at least 165°F, avoiding slow cookers, advises the U.S. Department of Agriculture .
  • Beyond immediate steps, experts say following these tips can reduce foodborne illness, limit waste and stretch grocery budgets by turning leftovers into several days of meals, while dispelling common food‑safety myths about refrigerating hot food and pie storage for home cooks and consumers.
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Food & Wine broke the news in on Wednesday, November 26, 2025.
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