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GC Genome Publishes Blood-Based Colorectal Cancer Screening Study in the American Journal of Gastroenterology

The AI-driven cfDNA blood test showed 90.4% sensitivity and 94.7% specificity in detecting colorectal cancer and advanced adenomas, offering a less invasive screening option.

  • Publication in The American Journal of Gastroenterology shows GC Genome's AI-based fragmentomics technology was validated for early colorectal cancer detection, with 90.4% sensitivity and 94.7% specificity.
  • As a screening alternative, the study suggests a convenient option to colonoscopy and fecal-based screening tests for earlier detection of colorectal cancer and advanced adenomas using a 10 mL blood sample.
  • In the trial, researchers enrolled 1,677 study participants, including 302 with CRC and 108 with AA, achieving CRC sensitivity of 90.4% and specificity of 94.7%.
  • It was reported that GC Genome will expand global clinical collaborations and screening applications, including a future ai-CANCERCH upgrade from six to ten cancers.
  • With CAP-accredited labs, GC Genome is positioned to scale testing, leveraging R&D emphasis and genetic diagnosis services for oncology, pre&neonatal, and rare diseases to expand global clinical capacity.
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PR Newswire broke the news in United States on Thursday, November 27, 2025.
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