US EditionFirst ALS Reversal Reported Using Brain Temperature Therapy
A 56-year-old woman with progressive ALS regained motor and cognitive functions after AI-guided brain temperature therapy, with no adverse effects reported in 11 months, researchers say.
- MIAMI, Dec. 04, 2025, BTT Medical Institute and btt Corp. announced the first documented total reversal of ALS using Computerized Brain‑Guided Intelligent Thermofebrile Therapy, reported in Diseases.
- Developed from the Brain‑Eyelid Thermoregulatory Tunnel, CBIT2 digitally reengineers fever therapy to activate heat shock proteins and clear misfolded TDP‑43 in ALS.
- Electromyography showed complete reversal of denervation, molecular biomarkers IL‑10 and NfL improved after two CBIT2 sessions, and cognitive and functional measures rose in Moira Papp.
- BTT Medical Institute said it will start formal clinical trials in early 2026 to test safety and reproducibility, while the report states Moira Papp no longer meets ALS criteria and stopped ALS medications.
- Amid a global brain‑health crisis, neurological disorders affect over three billion people worldwide, and Alzheimer's cost the U.S. $360 billion in 2024, framing a critical unmet need, Dr. M. Marc Abreu said this is "a paradigm shift" with potential for Alzheimer's, Parkinson's and related disorders.
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BTT Medical Institute Announces Unprecedented Case of Total Reversal of ALS through ...
MIAMI, Dec. 04, 2025 (GLOBE NEWSWIRE) -- BTT Medical Institute, in collaboration with btt Corp. (Brain Tunnelgenix Technologies Corp.), a medical technology company pioneering brain thermodynamics solutions, today announced the first documented case of total reversal of amyotrophic lateral sclerosis…
Globe Newswire
biospace.comBTT Medical Institute Announces Unprecedented Case of Total Reversal of ALS through Re-engineering of the Nobel Prize-Winning Fever Therapy into a Brain-Guided, Artificial Intelligence-Controlled ThermoFebrile Treatment
First video-documented ALS reversal marks a new era for brain health achieved through noninvasive computerized brain-temperature modulation, confirmed by...
Total Reversal of ALS Confirmed by EMG Normalization, Structural Reconstitution, and Neuromuscular–Molecular Restoration Achieved Through Computerized Brain-Guided Reengineering of the 1927 Nobel Prize Fever Therapy: A Case Report
Background: Neurological disorders are the leading cause of disability, affecting over three billion people worldwide.
Total Reversal of ALS Confirmed by EMG Normalization, Structural Reconstitution, and Neuromuscular-Molecular Restoration Achieved Through Computerized Brain-Guided Reengineering of the 1927 Nobel Prize Fever Therapy: A Case Report
This case provides the first documented evidence that ALS can be reversed through digitally reengineered fever therapy aligned with thermoregulation, which induces heat shock response and upregulates heat shock proteins, resulting in the patient no longer meeting diagnostic criteria for ALS and disc …
BTT Medical Institute claims first ever reversal of ALS via brain-guided fever therapy - Longevity.Technology - Latest News, Opinions, Analysis and Research
BTT Medical Institute says it has documented what it describes as the first confirmed case of total reversal of Amyotrophic … Continue reading "BTT Medical Institute claims first ever reversal of ALS via brain-guided fever therapy"
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