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FDA warns of ‘rare but severe itching’ after using popular allergy medications

  • A recent alert from the FDA highlights that individuals stopping regular use of the allergy treatments Zyrtec or Xyzal may experience intense itching, a rare side effect reported by hundreds after discontinuing the medications following prolonged daily use.
  • The warning follows reports from hundreds of people who experienced pruritus after taking cetirizine or levocetirizine daily for several months.
  • The FDA is reviewing the prescription versions to add a warning and has requested over-the-counter manufacturers to update their labels accordingly.
  • The agency said the itching is rare but can require medical attention and advised patients to consult their health professionals if symptoms occur.
  • The FDA recommended that anyone considering regular use of these allergy pills discuss this new risk with a healthcare provider before starting treatment.
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I have a sudden itching in my hands and legs, especially in the evenings, and when I get up I notice blisters that bursting into grains, with a thick texture. I have been having this disease for three years and it gives me trouble sitting down, because they have come out of my buttocks, and my job is to sit for many hours. My relatives tell me that they can be cancerous lesions. The medicine I take is loratadine and betamethasone, but I don’t fe…

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MedPage Today broke the news in New York, United States on Tuesday, May 20, 2025.
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