Estrogen and Alzheimer’s: New Research Points to Potential Brain Protection in Women - Top 50 Women Forum

Magic or realism? genetic variants seem to protect against Alzheimer’s disease

Piller and Smith in Science: Since 2023, an international research team known for finding rare genetic variants that shield against Alzheimer’s disease has dropped hints about its biggest prize yet. The scientists named it Macondo, in homage to the fictional Colombian town in One Hundred Years of Solitude, by Gabriel García Márquez, the master of magical realism who died with Alzheimer’s in 2014. Identified in the novelist’s sister, the mutation…

For 20 years, women were warned that hormone therapy raised their dementia risk. A study of 21,000 women just looked inside their autopsied brains and found the opposite - thesciverse

In 2002, a large clinical trial called the Women's Health Initiative published findings that changed how doctors and patients thought about hormone therapy. The study reported elevated risks of breast cancer, heart disease, and dementia in women taking combined hormone therapy. The reaction was swift and lasting. Hormone therapy prescriptions fell by more than 70% in the years that followed. Women who had been using it to manage menopause sympto…

Later-Life Estrogen Use Linked to Lower Dementia Risk

A large study has found an unexpected link between estrogen-only hormone therapy used later in life and a lower likelihood of dementia. Women who had used the treatment were less likely to receive a dementia diagnosis and were also less likely to show several signs of Alzheimer’s disease in their brains after death. The researchers […] The post Later-Life Estrogen Use Linked to Lower Dementia Risk appeared first on Knowridge Science Report.

Estrogen and Alzheimer’s: New Research Points to Potential Brain Protection in Women - Top 50 Women Forum

New research is drawing attention to a possible association between estrogen-only hormone therapy during menopause and a lower risk of dementia in women, while also highlighting the need for further research before the findings can be translated into treatment recommendations. The study, published in the scientific journal Neurology, examined medical data from 21,462 women, including 1,953 who had received estrogen-only hormone therapy. Research…

Stanford Study Links Estrogen-Only Hormone Therapy To 35% Lower Alzheimer's Disease Risk

A Stanford-led study reveals that women using estrogen-only hormone therapy show reduced Alzheimer's pathology and lower dementia diagnosis odds, highlighting the need for further research in this contested area.