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ESMO 2026 Preview | Mabwell to Present Clinical Results for Nectin-4-Targeting ADC 9MW2821 in ADC-Pretreated Triple-Negative Breast Cancer
Mabwell will present Phase II results for its Nectin-4-targeting ADC 9MW2821 at the 2026 European Society for Medical Oncology Congress.
The study evaluates 9MW2821 alone or with a PD-1 antibody in patients with advanced TNBC previously treated with a Topo I ADC.
Among 60 evaluable patients, the objective response rate was 30.0%, the disease control rate was 80.0%, and median progression-free survival was 3.7 months.
Mabwell reported no new safety signals, and described 9MW2821’s safety profile as manageable.