US EditionCancer blood test seven times more effective than current screening
The Galleri test detected early-stage cancers in over 50% of positive cases and ruled out cancer in 99.6% of people without the disease, US study shows.
- Grail's Pathfinder 2 trial showed the Galleri test screens for more than 50 cancers, detecting a cancer signal in 216 people with 133 confirmed diagnoses.
- Using DNA methylation patterns, Galleri test identifies cancer-specific methylation 'fingerprint' in blood to spot early disease signs, with modelling projections recommending annual screening from age 50.
- Specificity and localisation metrics indicate the test correctly excluded cancer in 99.6% of people testing negative, pinpointed the organ or tissue in 92% of cases, and 61.6% of patients with a detected 'cancer signal' received a diagnosis.
- Results showed a jump in detected cancers when combined with existing screening programmes, finding more than seven-fold more cancers within a year, with 53.5% at stages I–II and an NHS Galleri trial reporting next year.
- Experts emphasise the need for mortality-focused randomised data as Professor Clare Turnbull calls for endpoints, Professor Anna Schuh warns the test is wrong almost half the time, and cost estimates at current test price reach USD 174,000 per additional diagnosis.
84 Articles
84 Articles
Groundbreaking blood test can detect more than 50 cancers, Bay Area biotech says
A Bay Area biotech company is behind a potentially groundbreaking blood test that promises to be a game-changer in cancer detection, with the ability to discover more than 50 types of cancer even before symptoms appear.
Blood test can detect more than 50 kinds of cancer, new study suggests
A blood test for more than 50 types of cancer could significantly boost early detection and speed up diagnosis, according to a new study. Made by U.S. pharmaceutical company Grail, the Galleri test aims to find fragments of DNA in a person’s blood that can indicate the presence of a cancerous tumor. Among the cancers that the test can detect, many have no current screening programs. The PATHFINDER 2 study included more than 36,000 people aged …
Promising results from a North American cancer diagnosis study are resonating around the world. The Galleri advanced blood test, developed in the US, could speed up diagnosis for more than 50 types of cancer, most of which are not screened for.
Groundbreaking blood test detects 50 different types of cancer - 'Seven times as many as other screening programmes put together'
A Blood test has shown it can correctly confirm cancer in nearly two-thirds of positive cases, offering hope for earlier diagnosis across the UK.The Galleri test, currently being trialled by the NHS, successfully identified cancer in 61.6 per cent of people whose blood showed cancer signals during a major study.What makes this test particularly exciting is its ability to screen for more than 50 different types of cancer from a single blood sampl…
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