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Canadian researchers reach 'major milestone' in search for ALS treatment

  • On May 7, 2025, Canadian researchers at Sunnybrook Health Sciences Centre started a Phase 1 trial delivering drugs via ultrasound to six ALS patients, including Bill Traynor.
  • The trial addresses the blood-brain barrier, which blocks drug access despite drugs potentially treating ALS, a fatal neurodegenerative disease with no cure.
  • Traynor received immunoglobulin, an antibody therapy that suppresses inflammation, delivered precisely to his motor cortex using focused ultrasound, temporarily opening the barrier.
  • Researchers confirmed the immunoglobulin crossed to the target area and Traynor tolerated the procedure well, though they cautioned the trial is early-stage and not expected to produce treatments.
  • Investigators called this a major milestone enabling future drug testing to target ALS, and Traynor views the study as a source of hope despite his terminal diagnosis.
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Winnipeg Free PressWinnipeg Free Press
+4 Reposted by 4 other sources
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Canadian researchers reach 'major milestone' in search for ALS treatment

Breaking News, Sports, Manitoba, Canada

·Winnipeg, Canada
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sunnybrook.ca broke the news on Friday, May 9, 2025.
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