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Bayer’s Asundexian Reduced Recurrent Ischemic Stroke in OCEANIC-STROKE

February 19, 2026—Bayer recently reported that its oral factor XIa inhibitor asundexian reduced the risk of recurrent ischemic stroke in patients after noncardioembolic ischemic stroke or high-risk transient ischemic attack (TIA), meeting the primary efficacy endpoint of the phase 3 OCEANIC-STROKE trial, according to the company’s announcement. In the randomized trial, asundexian 50 mg once daily on top of antiplatelet therapy was associated wit…
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A research drug could open a new way in secondary stroke prevention, one of the leading causes of death and disability in the world. The results of the international phase III OCEANIC-STROKE trial indicate that the experimental asundexian anticoagulant developed by Bayer pharmaceuticals reduced the risk of a new ischemic stroke by 26% in patients who had already had a stroke, without increasing serious bleeding complications.

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Endovascular Today broke the news in on Thursday, February 19, 2026.
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