Antidepressant Escitalopram More Effective at Preventing Relapse, Analysis Finds
Researchers found escitalopram had 62% higher odds of sustained recovery than Prozac in a review of 20 antidepressants, while bupropion ranked worst.
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8 Articles
Study identifies antidepressants that get patients well and keep them well
Worldwide, nearly 6% of people experience depression. Many of them continue taking antidepressants after achieving symptomatic improvement, among other reasons to prevent a relapse of depression. An international team of researchers investigated which antidepressants, if any, can not only get patients well but also keep them well (sustained response).
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A review published in the scientific journal The Lancet Psychiatry suggests that some antidepressants, such as escitalopram and duloxetine, may be more effective than fluoxetine in improving the symptoms of depression and maintaining the benefits of long-term treatment. The research brings together the results of 115 randomized clinical trials of 21 antidepressants, with more than 30,000 participants, and constitutes the first comparison of the …
People starting an antidepressant are by no means always prescribed the best medication for their depressive symptoms. Radboudumc has now compiled a ranking of the most effective drugs. The best-known drug, fluoxetine, which many people know better as Prozac, turns out to be far from the best.
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