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Antengene to Present Latest Preclinical Results of ATG-207 (αCD3-TGF-β Bifunctional Fusion Protein) at ACR 2026
Antengene announced that it will present the latest preclinical results for ATG-207 at the 2026 American College of Rheumatology Annual Meeting in Orlando, Florida.
ATG-207 is a proprietary αCD3-TGF-β bifunctional fusion protein being developed for T cell–mediated autoimmune diseases.
Researchers created ATG-207 by adding a peptide-masked, TGFβRIII-biased TGF-β domain to an anti-CD3 antibody.
In mouse models, a surrogate version of ATG-207 showed therapeutic effects.