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Antengene to Present First Preclinical Data on ATG-207 (αCD3-TGF-β Bifunctional Fusion Protein) at EULAR 2026

The poster will detail receptor binding, T cell modulation and regulatory T cell induction in preclinical studies, with lower cytokine release in assays, company said.

  • On Wednesday, June 3, 2026, Antengene Corporation Limited announced it will present the first preclinical data for ATG-207 at the European Congress of Rheumatology in London from June 3 to 6.
  • Antengene developed ATG-207 to address T cell-mediated autoimmune diseases where existing anti-inflammatory therapies fail to eliminate pathogenic effector T cells and restore durable immune tolerance.
  • The program utilizes the proprietary AnTenGager platform, featuring '2+1' bivalent binding and TGFβRIII-biased activity, and preclinical studies demonstrated substantially lower proinflammatory cytokine release compared to unbiased fusion protein controls.
  • To date, Antengene has obtained 32 investigational new drug approvals in the U.S. and Asia, alongside new drug application approvals in 10 Asia Pacific markets, positioning the company across multiple regulatory jurisdictions.
  • The EULAR 2026 poster presentation scheduled for June 6, 2026, will detail ATG-207's receptor binding, T cell receptor modulation, and regulatory T cell induction in models of T cell-mediated autoimmune disease.
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Antengene to Present First Preclinical Data on ATG-207 (αCD3-TGF-β Bifunctional Fusion Protein) at EULAR 2026

SHANGHAI and HONG KONG, June 3, 2026 /PRNewswire/ -- Antengene Corporation Limited ("Antengene", SEHK: 6996.HK) , a leading innovative, commercial-stage global biotech company dedicated to discovering, developing and commercializing first-in-class and/or best-in-class medicines for autoimmune diseases, solid tumors and hematological…

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PR Newswire broke the news in United States on Wednesday, June 3, 2026.
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