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Antengene Licenses ATG-106 to K2 Therapeutics

  • Antengene has licensed ATG-106, a CDH6 x CD3 bispecific TCE, to K2 Therapeutics, expanding their collaboration around the AnTenGager® platform.
  • K2 Therapeutics will receive ATG-106 and a second TCE program enabled by the AnTenGager® platform, with K2's Chief Medical Officer expressing excitement about these therapies.
  • The license agreement includes upfront and near-term payments of about USD 20 million to Antengene, potential milestone payments up to USD 960.5 million, and tiered royalties on future net sales.
  • ATG-106 is designed to address safety and tolerability challenges found in first-generation TCEs in solid tumors.
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The Berkshire EagleThe Berkshire Eagle
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Antengene Announces Exclusive License Agreement with MPM BioImpact-Established K2 Therapeutics for ATG-106 and Option for Undisclosed Bispecific TCE

ATG-106 is a first-in-class CDH6 x CD3 bispecific T cell engager (TCE) in preclinical development for the treatment of solid tumors K2 Therapeutics, established by MPM BioImpact, obtains exclusive global rights to develop and commercialize ATG-106 outside Greater China Antengene…

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PR Newswire broke the news in United States on Monday, June 22, 2026.
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