Alumis Stock Nearly Doubles on Psoriasis Drug Trial, FDA Plans
Envudeucitinib achieved high skin clearance rates, with 74% reaching 75% lesion clearance, prompting Alumis to plan U.S. approval and a $175 million share offering.
- On Jan 6, 2026, Alumis said envudeucitinib met all endpoints in two Phase 3 trials and plans U.S. approval later this year.
- By the numbers, envudeucitinib helped 74% achieve PASI75 and around 65% reach PASI90 at week 24, targeting IL‑23 and IL‑17 pathways.
- Comparisons to J&J and Takeda show Alumis' envudeucitinib posting similar results and potentially being 'class‑leading' for TYK2 inhibition, competing with Bristol Myers Squibb's Sotyktu, which earned $126 million in the first nine months of 2025.
- Trading showed a dramatic market response, with trading volume 64.1 million shares and 3,077% above three‑month average, shares up nearly 82%, and Alumis announcing a $175.0 million offering of common stock.
- The focus is now on New Drug Application timing and competitive dynamics as envudeucitinib is tested in Crohn's disease and systemic lupus erythematosus with phase 2b results due in the third quarter of 2026.
11 Articles
11 Articles
Stock Market Today, Jan. 6: Alumis Shares Surge on Positive Phase 3 Psoriasis Data for Envudeucitinib
Alumis (NASDAQ:ALMS), which develops targeted therapies for immune-mediated diseases, closed Tuesday’s session at $16.23, up 95.31%. Trading volume reached 64.1 million shares, coming in about 3,077% above its three-month average of 2 million shares.Tuesday's move followed Phase 3 psoriasis data for envudeucitinib, which investors are treating as a potential commercial inflection point. The focus is now watching New Drug Application (NDA) timing…
Alumis reports positive Phase III data for envudeucitinib in plaque psoriasis
Alumis has announced positive top line data from its Phase III ONWARD1 and ONWARD2 clinical trials evaluating envudeucitinib in adults with moderate-to-severe plaque psoriasis.The post Alumis reports positive Phase III data for envudeucitinib in plaque psoriasis appeared first on Clinical Trials Arena.
Coverage Details
Bias Distribution
- 75% of the sources are Center
Factuality
To view factuality data please Upgrade to Premium



