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Alnylam, Inceptive Ink AI Deal Potentially Worth $2B

The three-year pact pairs Inceptive’s foundation models with Alnylam’s RNAi platform to speed siRNA design and includes milestone payments.

  • On Wednesday, Alnylam Pharmaceuticals and Inceptive Nucleics announced a strategic collaboration worth up to $2 billion to accelerate RNA interference drug discovery using artificial intelligence.
  • Inceptive CEO Jakob Uszkoreit noted that 'most drug design still works through a process of trial and error, testing thousands of molecules and hoping something sticks,' a limitation the partnership addresses.
  • Alnylam will pay $30 million upfront in cash and equity, gaining access to Inceptive's AI expertise and talent including co-founder Uszkoreit, who co-invented the Transformer architecture underlying ChatGPT.
  • CEO Yvonne Greenstreet, M.D., stated the company is 'thrilled to partner with Inceptive to push the boundaries' of RNAi medicine, supporting Alnylam's 2030 strategy for pipeline expansion.
  • Inceptive, founded in 2021, specializes in sequence-based medicine design including siRNA and peptides, bolstering Alnylam's global reach which currently spans more than 70 countries.
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Las Vegas SunLas Vegas Sun
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Alnylam and Inceptive Form Strategic AI Collaboration to Accelerate the Discovery of RNAi Therapeutics

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·Las Vegas, United States
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Alnylam, Inceptive sign up to $2 billion AI drug discovery deal

·New York, United States
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Reuters broke the news in New York, United States on Wednesday, June 3, 2026.
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