Breast Cancer May Hijack Nerves To Grow and Resist Treatment
3 Articles
3 Articles
Breast Cancer May Hijack Nerves To Grow and Resist Treatment
Triple-negative breast tumors may hijack immune cells to attract nerves that help the cancer grow. Nerves growing through a tumor may help an aggressive breast cancer survive, expand, and resist treatment. University of Oklahoma researchers have identified how triple-negative breast cancer may recruit those nerves by turning the body’s own immune cells into messengers. Networks [...]
AI-Designed Minibinders Target ERO1A–PDIA1 Redox Axis in Triple-Negative
Triple-negative breast cancer has long presented one of oncology’s most difficult challenges: it lacks the three molecular markers—estrogen receptor, progesterone receptor and HER2—that guide many targeted treatments. As a result, patients often rely on chemotherapy, immunotherapy or experimental approaches, while the disease’s aggressive biology and tendency to develop resistance continue to drive the search for […]
Researchers at the University of Oklahoma have identified a mechanism by which triple-negative breast cancer tumors recruit nerves, using immune cells as messengers. The discovery, published in the journal Cell Death & Differentiation, reveals how this interaction can promote tumor growth and resistance to treatments. Mechanism of nerve recruitment in tumors: Triple-negative breast cancer tumors attract immune cells called macrophages to their s…
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