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New Recall of Injected Penicillin May Put Gains Against Syphilis in Peril

UNITED STATES, JUL 16 – Pfizer is rationing Bicillin L-A after recalling contaminated lots, risking reversal of progress against a syphilis surge that increased tenfold since 2012, CDC data shows.

  • In 2023, Pfizer recalled certain lots of Bicillin L-A due to contamination with floating particles, causing a shortage of this key syphilis treatment in the United States.
  • The shortage occurred following reductions in funding for both national and local STD initiatives and complications related to stoppers from an outside supplier, which Pfizer is currently addressing through corrective measures.
  • Bicillin L-A is the recommended long-acting penicillin injection for treating syphilis during pregnancy, while reported cases of congenital syphilis in the United States have risen sharply from 335 in 2012 to over 3,800 in 2023.
  • Dr. Jeffrey Klausner warned this crisis "is a complete kick in the teeth" threatening syphilis control, while a CDC official expressed concern that funding cuts will cause drops in syphilis testing.
  • Pfizer plans to ration supplies until recovery and the National Coalition of STD Directors is gathering data to assess the recall's impact amid ongoing efforts to import equivalent antibiotics.
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New recall of injected penicillin may put gains against syphilis in peril

Pfizer announces a Bicillin L-A shortage following a recall, threatening syphilis treatment during pregnancy as congenital syphilis cases surge

·Milwaukee, United States
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KEYT broke the news in on Wednesday, July 16, 2025.
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