A Surprising Shift in Sniffing and Odor Perception Could Be a Key Sign of Parkinson's Disease

A surprising shift in sniffing and odor perception could be a key sign of Parkinson's disease

A new test that measures both how people describe odors and how they physically sniff them provides a way to distinguish Parkinson’s disease from other causes of smell loss. The findings suggest that people with Parkinson’s do not just lose their sense of smell, but experience a shift in how they perceive odors. This research was published in the journal npj Parkinson’s Disease. A reduced ability to detect and identify odors often appears years …

Parkinson's Disease Drug Dose Optimization Using Multi-Objective Reinforcement Learning

Parkinson's disease (PD) medication management requires balancing motor symptom control against adverse effects such as dyskinesia, making treatment decisions multi-dimensional and preference-sensitive. Most reinforcement learning (RL) approaches in healthcare optimize a single scalar objective, ...

Non-drug Treatments for Parkinson's Disease

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Trihexyphenidyl hydrochloride for Parkinson's disease

What is trihexyphenidyl hydrochloride for Parkinson’s disease? Trihexyphenidyl hydrochloride is an approved oral therapy that can help manage the symptoms of Parkinson’s disease. It is often used alongside levodopa. The motor and nonmotor symptoms of Parkinson’s arise when the nerve cells that produce dopamine, a chemical messenger in the brain (also called a neurotransmitter), gradually die. Dopamine works alongside other neurotransmitters, inc…