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Shingles vaccine linked to 24% lower dementia risk

  • The Shingrix shingles vaccine is linked to a 24% lower risk of dementia in adults aged 66 and older over a four-year period based on a study of over 500,000 people in skilled nursing facilities.
  • Among vaccinated individuals, 18.8% developed dementia compared to 24.6% of unvaccinated participants, suggesting one dementia case may be prevented for every 17 vaccinated people.
  • Researchers analyzed Medicare claims and electronic health records using target trial emulation methods to adjust for health differences.
  • Although the observational study cannot prove causation, researchers suggest potential neuroprotective effects of the vaccine and recommend randomized clinical trials for confirmation.
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The benefits of the Shingrix vaccine, given in two doses, could be comparable to those of daily treatment with blood pressure medications, say researchers. The current vaccine against the zoster zone seems to significantly reduce the risk of myocardial infarction and stroke, according to scientists, who claim that it could contribute to preventing ...

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Medscape broke the news in New York, United States on Tuesday, August 25, 2026.
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