Buck Institute and Georgetown Lead Effort Mapping Harmful Protein Changes Before Disease Begins

Buck Institute and Georgetown lead effort mapping harmful protein changes before disease begins

A research "super team" co-led by theBuck Institute for Research on Aging and Georgetown University has received an award of up to $51.7 million from the Advanced Research Projects Agency for Health (ARPA-H) to predict how disease-causing proteins misfold before irreversible damage occurs and use those predictions to develop novel diagnostics and treatments.

Scientists Receive Up to $51.7 Million to Predict Protein Misfolding Before

In an ambitious bid to catch disease at its molecular origins, a research consortium co-led by the Buck Institute for Research on Aging and Georgetown University has been awarded up to $51.7 million from the Advanced Research Projects Agency for Health (ARPA-H). The four-year effort, known as team SEEDS, will attempt something that has long eluded biomedical science: predicting how disease-causing proteins change shape and turn harmful before ir…