Researchers Investigate Viagra's Potential Role in Limiting Cancer Spread
Researchers found sildenafil reduced cancer spread in mice and linked use to 26% lower five-year death risk in men with cancer.
- Published in Cancer Research, a new study suggests sildenafil, the active ingredient in Viagra, may help limit cancer metastasis by disrupting the cholesterol supply cancer cells need to spread.
- Inhibiting the PDE5 enzyme, sildenafil increases cGMP levels, which reduces cholesterol transport within cells and creates a shortage to which cancer cells are particularly sensitive.
- Data from about 5 million Clalit Health Services members analyzed by researchers showed that cancer patients taking sildenafil often survived longer, particularly when paired with other medications.
- Prof. Ayelet Erez of the Weizmann Institute of Science found that combining sildenafil with statins restricts both existing and new cholesterol supplies, placing cancer cells under greater pressure.
- Following the July 14, 2026 publication, Erez emphasized the importance of considering a patient's metabolic state and existing medications when tailoring cancer therapies to treat the whole person.
22 Articles
22 Articles
Cancer patients who take erectile dysfunction and cholesterol medications have a lower risk of death, according to a population study.
Viagra, one of the best known drugs to treat erectile dysfunction, could add a new application in the fight against cancer. A study by the Weizmann Institute of Sciences (Israel), published in the journal Cancer Research, suggests that sildenafil, its active substance, could hinder metastases by preventing tumor cells from taking advantage of ... Continue reading "A study links the use of Viagra to greater survival in cancer patients"
A recent study revealed that Viagra not only treats erectile dysfunction, but could block the progression of cancer in your body; it knows how it does it.
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