Researchers Investigate Viagra's Potential Role in Limiting Cancer Spread
Researchers found sildenafil reduced cancer spread in mice and linked use to 26% lower five-year death risk in men with cancer.
- Published in Cancer Research, a new study suggests sildenafil, the active ingredient in Viagra, may help limit cancer metastasis by disrupting the cholesterol supply cancer cells need to spread.
- Inhibiting the PDE5 enzyme, sildenafil increases cGMP levels, which reduces cholesterol transport within cells and creates a shortage to which cancer cells are particularly sensitive.
- Data from about 5 million Clalit Health Services members analyzed by researchers showed that cancer patients taking sildenafil often survived longer, particularly when paired with other medications.
- Prof. Ayelet Erez of the Weizmann Institute of Science found that combining sildenafil with statins restricts both existing and new cholesterol supplies, placing cancer cells under greater pressure.
- Following the July 14, 2026 publication, Erez emphasized the importance of considering a patient's metabolic state and existing medications when tailoring cancer therapies to treat the whole person.
13 Articles
13 Articles
In world first, Israeli scientists find active ingredient in Viagra may stop cancer spread
Researchers say mouse models and data from 5 million health fund members show erectile dysfunction drug and statins may improve outcomes by blocking cholesterol needed for cells to metastasize
Viagra could do more than advertised as study reveals surprising health superpower - NEW YORK TIMES POST
NEWYou can now listen to Fox News articles! Viagra could do more than give men a boost in the bedroom, as new research suggests it may have benefits for cancer patients. The prescription medication, which is manufactured and distributed by Viatris, is commonly used to treat erectile dysfunction by increasing blood flow during sexual stimulation. It was originally developed to treat high blood pressure and chest pain caused by reduced blood flow …
Viagra could do more than advertised as study reveals surprising health superpower
Viagra's active ingredient sildenafil, a PDE5 inhibitor used for erectile dysfunction, may prevent cancer metastasis by limiting cholesterol access in cancer cells, a new study finds.
The Dallas Express News
wbap.comViagra’s Side Hustle? Slowing Cancer’s Spread, Research Finds
A study recently published in the journal Cancer Research reports that sildenafil, the active ingredient in Viagra, may restrict cancer cells’ ability to metastasize by disrupting their cholesterol processing. The research, led by scientists at the Weizmann Institute of Science in Israel and co-authored by investigators from the U.S. National Cancer Institute, drew on laboratory experiments, animal models, human cancer cell cultures, and an anal…
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