NFL Week 5: Unbeaten 49ers Face Sternest Test as Eagles Seek to Arrest Slump in London

NFL Week 5 predictions, picks, win probabilities for games this week

NFL Week 5: Unbeaten 49ers face sternest test as Eagles seek to arrest slump in London

The 49ers face arch rivals the Seahawks in the biggest game of the NFL week 5 slate.

PFT's Week 5 2026 NFL picks

Our take on all 15 games to be played this weekend.

The Playbook: Shadow Reports, lineup locks and projected scores for Week 5

An all-encompassing look at the matchups to exploit or avoid and lineup locks in fantasy, as well as projected scores for all NFL games.

NFL Week 5 picks: Experts face off on Buccaneers at Cowboys, 49ers at Seahawks and more

Getty Images We are already five weeks into the 2026 NFL regular season. Can you believe it? This week, the Philadelphia Eagles and Jacksonville Jaguars face off in London, the San Francisco 49ers will play the reigning Super Bowl champion Seahawks in Seattle, and Josh Allen takes on Matthew Stafford on “Monday Night Football.” There were 23 games decided by one score over the past two weeks, which is tied for the most in a two-week span in NFL …

NFL Week 5 Pick 'Em: Cowboys look to dominate Bucs in primetime

We're now one month into the NFL season, and teams are beginning to separate themselves from the pack. Evan Davidson runs down the Week 5 slate to help you make your picks.