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FDA Approves First Non-Opioid Painkiller in Over Two Decades

  • The U.S. Food and Drug Administration approved Vertex Pharmaceuticals' Journavx, the first non-opioid painkiller in over two decades, for short-term pain relief following surgery or injuries.
  • Two studies indicated that Journavx provided more relief than a placebo but did not outperform a common opioid-acetaminophen combination pill.
  • Vertex's drug works by blocking proteins that trigger pain signals rather than binding to brain receptors like opioids.
  • Experts express cautious optimism about Journavx's potential, noting its unique mechanism of action and reduced risk of addiction compared to opioids.
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