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China · ChinaSymbiotic nitrogen fixation in legume nodules requires substantial energy investment from host plants, and soybean (Glycine max (L.) supernodulation mutants show stunting and yield penalties due to overconsumption of carbon sources. We obtained soybean mutants differing in their nodulation ability, among which rhizobially induced cle1a/2a (ric1a/2a) has a moderate increase in nodule number, balanced carbon allocation, and enhanced carbon and nit…See the Story
Genetically optimizing soybean nodulation improves yield and protein content
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Quantifying the stochastic component of epigenetic aging
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Finland · FinlandForest growth varies across landscapes due to the intricate relationships between various environmental drivers and forest management. In this study, we analysed the variation of tree growth potential across a landscape scale and its relation to soil moisture. We hypothesised that soil moisture conditions drive landscape-level variation in site quality and that intermediate soil moisture conditions demonstrate the highest potential forest produc…See the Story
Tree growth potential and its relationship with soil moisture conditions across a heterogeneous boreal forest landscape
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Redox-neutral electrochemical decontamination of hypersaline wastewater with high technology readiness level
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NatureAge-related changes in DNA methylation (DNAm) form the basis of the most robust predictors of age—epigenetic clocks—but a clear mechanistic understanding of exactly which aspects of aging are quantified by these clocks is lacking. Here, to clarify the nature of epigenetic aging, we juxtapose the dynamics of tissue and single-cell DNAm in mice. We compare these changes during early development with those observed during adult aging in mice, and c…See the Story
Nature of epigenetic aging from a single-cell perspective
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Development and multinational validation of an algorithmic strategy for high Lp(a) screening
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Coronavirus · ChinaThe uptake of COVID-19 booster vaccination among older adults in China is suboptimal. Here, we report the results of a parallel-group cluster-randomized controlled trial evaluating the efficacy of promoting COVID-19 booster vaccination among grandparents (≥60 years) through a health education intervention delivered to their grandchildren (aged ≥16 years) in a Chinese cohort (Chinese Clinical Trial Registry: ChiCTR2200063240 ). The primary outcom…See the Story
Influence of grandchildren on COVID-19 vaccination uptake among older adults in China: a parallel-group, cluster-randomized controlled trial
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Tracking single-cell evolution using clock-like chromatin accessibility loci
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