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Study: Some Suicide Cases Had No Typical Prior Warning Signs

  • On Nov. 26, 2025, University of Utah researchers reported in JAMA Network Open that about half of suicide deaths show no known history of suicidal thoughts or behaviors, with Hilary Coon noting many cases lack typical warning signs.
  • Public-Health practice focused on depression, with Coon explaining `A tenet in suicide prevention has been that we just need to screen people better for associated conditions like depression,' and she cautioned expanded depression screening 'might not help' some at risk.
  • Analyzing more than 2,700 genetic records, researchers found the hidden group had fewer psychiatric diagnoses and genetic risks for anxiety, depression, Alzheimer's disease, and post-traumatic stress disorder.
  • Clinical follow-up work seeks to investigate chronic pain, inflammation and respiratory diseases, aiming to help doctors identify high-risk individuals earlier even without expressed suicidal thoughts.
  • Looking beyond genes, researchers emphasized there is no single suicide "gene", are studying protective traits to understand resilience, and highlighted the 988 Lifeline for crisis support.
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UPI broke the news in Washington, United States on Wednesday, November 26, 2025.
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