Sperm tails and male infertility: Critical protein revealed via ultrastructure expansion microscopy

Sperm tails and male infertility: Critical protein revealed via ultrastructure expansion microscopy

Male infertility is a major issue worldwide and its causes remain unclear. Now, an international team of researchers led by Hiroki Shibuya at the RIKEN Center for Biosystems Dynamics Research (BDR) in Japan has discovered a key structure in the germ cells of male mice, that when disturbed, leads to deformations in sperm flagellum—the tail that allows sperm to swim.