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How the Brain Protects Itself From Alzheimer's Disease

Researchers found Glyoxalase 1 (GLO1) protein activity rises in young brains to counter calcium toxicity but declines with age, reducing protection against Alzheimer’s disease.

Summary by Medical Xpress
High levels of calcium are toxic to cells and contribute to loss of neurons in Alzheimer's disease. A new study published in JCI Insight identifies a mechanism through which the young brain protects itself against high calcium levels, and it could help scientists learn how to protect the brain from this devastating neurodegenerative condition.

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Futurity broke the news in on Tuesday, December 2, 2025.
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