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Healthy babies born in Britain after scientists used DNA from three people to avoid genetic disease

UNITED KINGDOM, JUL 19 – The UK’s three-person IVF technique helped seven women at high risk produce eight healthy babies with a 36% pregnancy success rate, reducing mitochondrial disease transmission.

  • A report in The New England Journal of Medicine shows, eight babies in the UK were born using the three-person IVF technique , reported researchers.
  • Mitochondrial disorders affect between 1 in 6,000 and 1 in 8,000 live births, with mutations causing blindness, seizures, and death, as mitochondrial DNA makes up about 1% of cellular DNA.
  • The procedure involved removing the nucleus from a fertilized egg with defective mitochondria, using eight babies from seven women, all showing no or very low levels of mitochondrial DNA mutations.
  • The mother of a baby girl said, `“After years of uncertainty this treatment gave us hope – and then it gave us our baby,”` in an emotional reaction.
  • Professor Carroll said studies should give Australia momentum to follow suit; he hopes to obtain their first licence from the NHMRC’s Embryo Research Licensing Committee, supported by $15 million from the Medical Research Future Fund in 2023.
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British researchers have planted fertilized cell nuclei in the egg cells of female donors. The process can protect newborns from certain hereditary diseases, but it is currently not approved in Switzerland and Germany.

·Zürich, Switzerland
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In order to avoid a hereditary disease, an in vitro fertilization technique used the genetic material of a donor, in addition to those of mother and dad. The procedure, however, involved the formation and then the rejection of a healthy embryo.In Britain there are eight children born without a disease.

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The experts have been waiting for this data: eight children were born in the UK, who were genetically descended from three parents after a mitochondria donation. The evaluation shows that the children are well-being so far. By Veronika Simon.

·Hamburg, Germany
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The Telegraph broke the news in London, United Kingdom on Wednesday, July 16, 2025.
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