Discovery that microglia can be effectively replaced could transform cell therapy for brain diseases

Discovery that microglia can be effectively replaced could transform cell therapy for brain diseases

An international research team led by Professor Kiavash Movahedi from the Brussels Center for Immunology at the Vrije Universiteit Brussel has published unexpected results in the journal Immunity. Their study sheds new light on the possibility of effectively replacing defective microglia—the brain's immune cells—marking a potential breakthrough in the treatment of neurodegenerative diseases such as Alzheimer's and Parkinson's.

Microchips in Brains Might be Too Far  – NYCTastemakers

The thought of implanting robotic enhancements into our bodies has always been a concept of science fiction, but things like Neuralink and other projects hit us with the realization that this is now a possibility. More specifically, putting a microchip into our brains is in early development and might be something that allures interest. However, […]

A 3D Human iPSC-Derived Multi-Cell Type Neurosphere System to Model Cellular Responses to Chronic Amyloidosis - Science in Vancouver

Alzheimer’s disease (AD) is characterized by progressive amyloid beta (Aβ) deposition in the brain, with eventual widespread neurodegeneration. While the cell-specific molecular signature of end-stage AD is reasonably well characterized through autopsy material, less is known about the molecular pathways in the human brain involved in the earliest exposure to Aβ. Human model systems that not only replicate the pathological features of AD but als…