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CureGene Unveils Groundbreaking Preclinical Data for CG-0416, a Novel Oral Non-GLP-1 Therapy, at Obesity Week 2025

  • CureGene Pharmaceuticals announced groundbreaking preclinical data for CG-0416, a novel oral non-GLP-1 weight-loss agent, at Obesity Week 2025.
  • CG-0416 shows high-quality weight loss in diet-induced obese mice, both alone and combined with GLP-1 receptor agonists.
  • The combination therapies revealed synergistic effects, demonstrating that CG-0416 with other agents provided greater results than each drug alone.
  • CureGene's data confirms CG-0416's potential as a next-generation weight-loss therapy and validates the efficiency of its Jade prodrug technology platform.
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The Berkshire EagleThe Berkshire Eagle
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CureGene Unveils Groundbreaking Preclinical Data for CG-0416, a Novel Oral Non-GLP-1 Therapy, at Obesity Week 2025

CG-0416, a highly liver-targeted THR-β agonist, demonstrates high-quality weight loss by reducing fat mass while preserving muscle, both as a monotherapy and in combination with GLP-1 RAs.

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PR Newswire broke the news in United States on Tuesday, November 11, 2025.
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