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USC Visits Nebraska in Big 10 Game of the Week

USC and Nebraska both seek College Football Playoff spots while Ohio State aims to extend its 11-game winning streak against a struggling Penn State, sportsbook odds show.

  • On Saturday, No. 23 Southern California visits Nebraska Cornhuskers at 7:30 p.m. ET while No. 1 Ohio State Buckeyes host Penn State Nittany Lions at noon ET with College Football Playoff implications.
  • The Nittany Lions, reeling from recent losses, have lost four straight games including firing James Franklin, leading to their undercard designation at No. 1 Ohio State Buckeyes.
  • According to BetMGM Sportsbook, USC is a 6 1/2-point road favorite and Ohio State a 20 1/2-point favorite; USC leads FBS with 326.1 passing yards per game while Nebraska allows 127.5.
  • Ohio State, riding an 11-game streak, brings recent dominance over Penn State while the Nittany Lions start Ethan Grunkemeyer after Drew Allar's season-ending injury.
  • Conference stats show that four of the top six FBS total defenses come from the Big Ten Conference, while No. 23 Southern California's lone Top 25 matchup remains on Nov. 22.
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LAFB Network broke the news in on Wednesday, October 29, 2025.
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