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Amy Schumer Reveals Side Effect of “Botched" Colonoscopy

Schumer said the procedure left her feeling off as she discussed weight loss, Cushing syndrome and a recent split from Chris Fischer.

  • During a recent 'Not Skinny But Not Fat' podcast event, Amy Schumer revealed that a 'botched colonoscopy' left her 'not feeling very sexual.'
  • Schumer previously confirmed a 2024 diagnosis of exogenous Cushing Syndrome, a hormonal condition causing weight gain and facial puffiness that she discovered after online comments about her appearance.
  • Separated from estranged husband Chris Fischer, Schumer and their 7-year-old son Gene confirmed their breakup in December after almost eight years of marriage.
  • Despite these difficulties, Schumer emphasized she feels 'happier than I've ever been before' while embracing a new chapter following her separation and health journey.
  • Clarifying that her weight loss is unrelated to her marriage's demise, Schumer noted she recently lost 50 pounds to address symptoms of her hormonal disorder.
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The actress clarified, however, that her mood has not been affected.

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US Magazine broke the news in United States on Sunday, May 17, 2026.
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