Published 14 days ago

CRISPR gene editing shows promise for treating individuals with a form of inherited blindness

A clinical trial of CRISPR gene editing in 14 individuals with inherited blindness proved safe and yielded measurable improvements in 11 participants.
All 14 participants, aged 10 to 63, had Leber Congenital Amaurosis due to mutations in the CEP290 gene.
Eleven participants saw improvements in various outcomes, with four having improved visual acuity and six showing enhanced cone-mediated vision.

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CNN

Experimental gene therapy restores some vision in patients with inherited blindness

A treatment that used CRISPR was found to be safe and efficacious in improving vision among a small sample of patients with inherited blindness

14 days ago·Atlanta, United States

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Deutsche Welle

CRISPR gene editing trial treats inherited blindness

Researchers have used a CRISPR-Cas9 tool to restore vision in adults and children with congenital blindness. The researchers said they hoped to soon cure the condition.

14 days ago·Germany

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Medical Xpress

CRIPSR gene editing leads to improvements in vision for people with inherited blindness, clinical trial shows

Results from a clinical trial of CRISPR gene editing in 14 individuals with a form of inherited blindness show that the treatment is safe and led to measurable improvements in 11 of the participants treated. The Phase I/II trial called BRILLIANCE, was led by principal investigator Eric Pierce, MD, Ph.D., of Mass Eye and Ear, a member of the Mass General Brigham health care system. Findings are reported May 6 in The New England Journal of Medicin…

14 days ago

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News Medical

CRISPR gene editing shows promise for treating individuals with a form of inherited blindness

Results from a groundbreaking clinical trial of CRISPR gene editing in 14 individuals with a form of inherited blindness show that the treatment is safe and led to measurable improvements in 11 of the participants treated.

13 days ago·United States

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Aristegui Noticias

Medical Breakthrough: CRISPR Therapy Offers Hope in Hereditary Blindness

This trial marks the first time that CRISPR technology has been used for gene editing within the human body.

13 days ago

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Science Daily

Participants of pioneering CRISPR gene editing trial see vision improve

About 79% of clinical trial participants experienced measurable improvement after receiving experimental, CRISPR-based gene editing that is designed to fix a rare form of blindness, according to a new article.

13 days ago·United States

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CRISPR gene editing shows promise for treating individuals with a form of inherited blindness

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Experimental gene therapy restores some vision in patients with inherited blindness

Experimental gene therapy restores some vision in patients with inherited blindness

CRISPR gene editing trial treats inherited blindness

CRISPR gene editing trial treats inherited blindness

CRIPSR gene editing leads to improvements in vision for people with inherited blindness, clinical trial shows

CRIPSR gene editing leads to improvements in vision for people with inherited blindness, clinical trial shows

CRISPR gene editing shows promise for treating individuals with a form of inherited blindness

CRISPR gene editing shows promise for treating individuals with a form of inherited blindness

Medical Breakthrough: CRISPR Therapy Offers Hope in Hereditary Blindness

Medical Breakthrough: CRISPR Therapy Offers Hope in Hereditary Blindness

Participants of pioneering CRISPR gene editing trial see vision improve

Participants of pioneering CRISPR gene editing trial see vision improve

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